Aperture

Neuromuscular · Rare

Duchenne muscular dystrophy

Updated August 2026 · DMD (dystrophin, Xp21)

Model levers

Custom per indication. These sliders re-cut the published funnel — they do not invent a claims extract.

Funnel · US

Prevalent DMD (males)17,500

Diagnosed and in care14,800

Ambulatory7,200

Non-ambulatory7,600

On corticosteroid SOC11,800

Skip-amenable (51/53/45/44)5,200

Elevidys-eligible today4,100

Mutation class

  • Exonic deletions65%
  • Duplications11%
  • Point / small mutations24%

Skip amenability

  • Exon 51 skip-amenable13%
  • Exon 53 skip-amenable8%
  • Exon 45 skip-amenable8%
  • Exon 44 skip-amenable6%
  • Other skip / none65%

Stage

  • Early ambulatory (≤7y)22%
  • Late ambulatory24%
  • Early non-ambulatory28%
  • Late non-ambulatory26%