Neuromuscular · Rare · teaser

Spinal muscular atrophy

Updated August 2026 · SMN1 (5q)

Teaser case. Selected price and peak-sales fields are held for a paid Brief — the rest is the method.

By phase

  • Phase 31
  • Phase 21

Classify

  • Biologic1
  • ASO / exon skip1
AssetSponsorPhaseModalityPopulationSignal
Muscle-directed (myostatin / troponin)

Residual weakness

SeveralPhase 2BiologicTreated SMA with residual deficit held
Higher-dose nusinersen

SMN2 splice

BiogenPhase 3ASO / exon skipSMA on or naive to Spinraza